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Crystal structure of variola virus virulence factor F1L in complex with human Bak BH3 domain

NIAID Data Ecosystem2026-05-01 收录

病毒毒力因子结构

细胞凋亡调控

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https://www.rcsb.org/structure/5AJK 数据链接链接失效反馈

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Crystal structure of variola virus virulence factor F1L in complex with human Bak BH3 domain

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2024-01-10

脓毒症治疗

细胞凋亡调控

BackgroundSevere sepsis and septic shock are major causes of morbidity and mortality worldwide. In experimental sepsis there is prominent apoptosis of various cell types, and genetic manipulation of d

NIAID Data Ecosystem60

Viral Bcl-2 homologs and their effect on the intrinsic apoptotic pathway.

病毒免疫逃逸

细胞凋亡调控

Viral Bcl-2 homologs and their effect on the intrinsic apoptotic pathway.

Figshare2023-12-13 更新20

Amyloid Beta-Mediated Epigenetic Alteration of Insulin-Like Growth Factor Binding Protein 3 Controls Cell Survival in Alzheimer's Disease

阿尔茨海默病表观遗传机制

细胞凋亡调控

Swedish double mutation (KM670/671NL) of amyloid precursor protein (APP) is reported to increase toxic amyloid β (Aβ) production via aberrant cleavage at the β-secretase site and thereby cause early-o

NIAID Data Ecosystem20

Supplementary Dataset1 and 2

N端乙酰化

细胞凋亡调控

N-terminal acetyltransferase B (NatB) is a major contributor to the N-terminal acetylome and is implicated in several key cellular processes including apoptosis and proteostasis. However, the molecula

Figshare2024-07-10 更新40

NIH/NIAID GM-CSF Modulates Global Changes in Neutrophil Gene Expression. Homo sapiens

细胞凋亡调控

GM-CSF信号转导

PMNs were isolated from venous blood of healthy individuals in accordance with a protocol approved by the Institutional Review Board for Human Subjects, National Institute of Allergy and Infectious Di

NIAID Data Ecosystem20

Crystal structure of variola virus virulence factor F1L in complex with human Bak BH3 domain

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