Supporting data for “ESTROGEN ACTIVATION ON HISTONE H3 LYSINE 79 DIMETHYLATION MEDIATED MENIN AND CHROMATIN INTERACTION IN BREAST CANCER"

This dataset is my thesis.In order to understand the dynamics between epigenetic regulation and hormone receptor interactions, proteomic and genomic approaches will be used to explore the effects of oestrogen activation on H3K79me2-mediated Menin/chromatin interactions as well as the mechanism of Menin - DOT1L - ERalpha interactions with chromatin in breast cancer cells.We designed several experiments such as chromatin immunoprecipitation (ChIP).The dataset includes the results of qPCR analyses for ChIP, western blot data relevant to the project, and datasets from anti-Menin, anti-DOT1L and anti-ERalpha co - IP experiments resolved by mass spectrometry.