Nascent proteomics profiling reveals NNMT as a regulator to promote drug resistance in lung cancer
收藏国家人口健康科学数据中心2026-06-01 收录
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https://www.ncmi.cn/phda/dataDetails.do?id=CSTR:17970.11.A001G.202502.94.V1.0
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资源简介：
In this work, we adopted a workflow including metabolic labeling, TAD-resin enrichment and MS quantification for a comprehensive understanding the changes of nascent proteins at the initial stage of drug treatment. Our investigation of nascent proteome alterations provided new insights into immediate responses of cancer cells to AZD9291 treatment, highlighting NNMT as a potential therapeutic target.
提供机构：
北京蛋白质组研究中心
创建时间：
2024-11-11
