Targeting KRASG12V mutations with HLA class II restricted TCR for the immunotherapy in solid tumors

To investigate the sequences of TILs, the sorted T cells were used for the following TCR sequencing analysis by 10X genomics Single Cell Sequencing. For the quality inspection and counting of single cell suspension, the cell survival rate is generally required to be more than 80%. Gene expression profiling analysis of single cell sequencing data for B13 TILs clontypes.