Clinical Efficacy of Modified San'ao Decoction and Erchen Decoction for Esophageal Dysphagia (Shi Bi) with Phlegm-Dampness and Blood Stasis Syndrome

This protocol describes a reproducible clinical workflow for evaluating modified San’ao Decoction and Erchen Decoction combined with camrelizumab and anlotinib in patients with advanced esophageal squamous cell carcinoma presenting with esophageal dysphagia and phlegm-dampness/blood-stasis syndrome. The protocol standardizes patient screening, randomization, decoction preparation, treatment administration, tumor-response assessment, TCM syndrome scoring, serum tumor-marker testing, flow-cytometric immune profiling, safety monitoring, and statistical analysis.