Tle2

ENCODES a protein that exhibits transcription corepressor activity (ortholog); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); neutropenia (ortholog); progressive myoclonus epilepsy 9 (ortholog); FOUND IN focal adhesion (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine

编码一种表现出转录共抑制活性（同源）的蛋白质；参与经典Wnt信号通路（同源）的负向调控；DNA模板转录的负向调控（同源）；与神经发育障碍（同源）相关；中性粒细胞减少症（同源）；进行性肌阵挛性癫痫9型（同源）；存在于焦点粘附（同源）；核体（同源）；核质（同源）；与（+）-五味子素B、17β-雌二醇、2,3,7,8-四氯二苯并-对-二噁英相互作用。