Interaction of NCAM1 with Neurocan

NCAM1 bind all major components of neurocan (N-terminal, central and C-terminal regions as well as CS chains), a brain-specific chondroitin sulfate proteoglycan. This molecule interferes with homophilic NCAM1 interactions and inhibits neuronal adhesion and neurite outgrowth.

NCAM1与神经节苷聚糖（N-端、中央区域及C-端区域以及CS链）的所有主要成分结合，该分子为脑特异性硫酸软骨素蛋白聚糖。此分子干扰同源NCAM1相互作用，并抑制神经元粘附及神经突生长。