Whole genome sequencing of Russian endemic M. tuberculosis strains

38 M. tuberculosis clinical isolates were sequenced to study the genomic organization for Russia endemic M. tuberculosis strains. Project participants are Research Institute of Physical-Chemical Medicine, Moscow;Scientific and Clinical Antituberculosis Center of Moscow Government Health Department, Moscow; Research Institute of Phthisiopulmonology, St. Petersburg; St. Petersburg Pasteur Institute, St. Petersburg; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow,Russia. All isolates were sequenced using the GS FLX+ System (Roche) and belong to three different genetic families (Beijing, Ural and LAM). This work is supported by 16.522.11.2003 grant of the Ministry of Education and Science of the Russian Federation for “Development and production of operative embodiments of diagnostic kit based on feature of the genomic organization for Russia endemic M. tuberculosis strains and suitable for the detection of drug-resistant tuberculosis”