Epistasis between promoter activity and coding mutations shapes gene evolvability
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
We performed a deep mutational scanning of the DfrB1 dihydrofolate reductase enzyme at different expression levels. We observed that the deleteriousness of mutational effects depends on the expression level.
创建时间：
2022-05-25
