We developed an experimental model system in mice, in which microglia can be depleted selectively and temporarily from the prefrontal cortex (PFC) during a defined window of adolescence (6 weeks of ag
Over 8000 high-qualified CD45IV-DAPI-CD45+ dura cells were sorted for single cell RNA sequencing; 13 cell populations were identified, Including T cells, B cells ,NK cells, monocytes, erythroid cells,
Sequencing of TRPV1+ neurons in jugular-nodose complex (JNC) in a mouse model of air pollution-exacerbated allergic inflammation. Overall design: TRPV1-cre/wt::tdTomato-fl/wt mice were sensitized via
3D viSNE representation of microglial modules: DAM (Red) and Homeostatic (Black) genes identified by single-cell RNAseq mapped to WGCNA modules. (HTML 3818 kb)