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资源简介：
WGS for off-target dectection
应用场景：
创建时间：
2022-05-10
相关数据集
gene-editing experiments in model cell lines
gene-editing experiments to measure on/off-target modification of endogenous genomic loci using next-generation sequencing (GUIDE-SEQ)
NIAID Data Ecosystem90
CaS2OT5_F1Sanger Sequencing results for the off-targets and CASR gene in F1 and F2 generation
Sanger sequencing results from the off-target analysis CaS2OT5_F1
Figshare2023-07-21 更新50
In vivo CRISPR-Cas gene editing with no detectable genome-wide off-target mutations
CRISPR-Cas genome-editing nucleases hold substantial promise for human therapeutics but identifying unwanted off-target mutations remains an important requirement for clinical translation. For ex vivo
NIAID Data Ecosystem40
High-throughput sequencing data of eeCas9 and eeBE of file6
Evaluation of the off-target efficiency of eeABEmax and ABEmax by HTS analysis in 293T cells.
NIAID Data Ecosystem60
Additional file 1 of The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis
Additional file 1: Table S1 Predicted and candidate off-target mutations.
NIAID Data Ecosystem40
