aNasal lavages were collected from age-matched or clinical hamsters with HY TME. For bioassay, 50 µl of nasal lavage was inoculated into 3 to 6 hamsters per sample and the duration until onset of clin
Leptospirosis, a zoonotic infection with worldwide prevalence, is caused by pathogenic spirochaetes of Leptospira spp., and exhibits an extremely broad clinical spectrum in human patients. Although pr