Crude associations of biomarkers and the CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc and HAS-BLED score with unfavourable 30-day outcome of ischemic stroke, predictive ability of each biomarker or score, and pairwise comparisons of each biomarker and stroke risk score predictive ability.
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OR, Odds Ratio; CI, Confidence Interval. Only biomarkers with p<0.01 regarding unfavourable 30-day functional stroke outcome are shown. CRP, C-reactive protein; WBC, white blood cell count; CrCl, creatinine clearance; CHA2DS2-VASc, congestive heart failure or left ventricular ejection fraction ≤40%, hypertension, age ≥75 years, diabetes mellitus, prior stroke or TIA, vascular disease (including myocardial infarction and peripheral artery disease), age >65 years, female gender (1 point each, age ≥75 years and prior stroke/TIA 2 points each); CHADS2, congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, prior stroke or TIA (1 point each, prior stroke/TIA 2 points); HAS-BLED, hypertension, abnormal renal or liver function, prior stroke, labile INRs (International Normalized Ratio), elderly (>65 years), concomitant drugs or alcohol use. Crude associations of biomarkers and the CHADS2, CHA2DS2-VASc and HAS-BLED score with unfavourable 30-day outcome of ischemic stroke, predictive ability of each biomarker or score, and pairwise comparisons of each biomarker and stroke risk score predictive ability.
