Whole genome sequence analysis of equid herpesvirus type 2 field isolates reveals high levels of genomic diversity and recombination

This project aimed to investigate EHV2 genome variation and recombination by the determination and analysis of the full genome sequences of historical (archived) and contemporary EHV2 isolates from Australian horses. Herpesvirus genome diversification and virus evolution can be driven by recombination, and our findings are consistent with recombination being a key mechanism by which EHV2 genomes may vary and evolve.