High density Anxiety Network (anxiety-network-all)
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An a priori anxiety network, based on a comprehensive review of anxiety literature, combining literature from humans, both Parkinson's Disease and non-Parkinson's disease groups, and animal models. This network will be used in a region of interest analysis in a neuroimaging study characterising the microstructural basis of anxiety in early Parkinson's disease. It will be used alongside a Parkinson's Anxiety Network (10.5281/zenodo.17174506). This network was updated in September 2025 and replaced a previous version originally published in November 2024. Following advice from an advisory thesis committee, a systematic review of PD anxiety neuroannatomical literature was conducted to inform the network, replacing a previous narrative review. This resulted in small changes to the annatomical nodes of the network. The update includes the addition of the bilateral orbital gyrus (split into 5 subregions) and the bilateral substantia nigra pars compacta and reticulata. All other regions remain the same.



