Role of endothelial SOCS3 in the transcriptional response to LPS

Translating affinity purification (TRAP)-mediated analysis of kidney endothelial translatome of bulk kidney RNA-seq from mice 15 hours after an intraperitoneal challenge with 250 micrograms of LPS per mouse. Overall design: Total RNA from kidney or endothelial especific. Four groups: WT+Saline, WT+LPS, SOCS3iEKO+Saline, SOCS3iEKO+LPS