Forrest plot of odds ratios (ORs) for the association of E-cadherin with clinicopathological features.

A. ORs with corresponding 95% CIs of the E-cadherin expression with differentiation grade. OR<1 suggested that unfavorable parameters for the group with negative/decreased E-cadherin expression and downregulated E-cadherin expression was associated with poor differentiation of CRC. B. ORs with corresponding 95% CIs of the E-cadherin expression with Dukes' stages. OR<1 indicated that low E-cadherin expression was associated with advanced Dukes' stage of CRC. C. ORs with corresponding 95% CIs of the E-cadherin expression with lymphnode metastasis. D. ORs with corresponding 95% CIs of the E-cadherin expression with distant metastasis.