Lipocalin-2 deficiency attenuates acute lung inflammation
收藏NIAID Data Ecosystem2026-05-01 收录
官方服务：
资源简介：
Lipocalin-2 promotes acute lung inflammation Overall design: WT(control), WT LPS(sample)
应用场景：
创建时间：
2023-06-01
相关数据集
A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression. A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
BMDMs were generated via differentiation of bone marrow cells in culture media containing m-CSF for 7 day. Upon differentiation, BMDMs were left untreated or stimulated with LPS, IFNa, PGE2, LPS+PGE2,
NIAID Data Ecosystem70
Targeted transcriptomic analysis of C57BL/6 and BALB/c mice during progressive chronic Toxoplasma gondii infection reveals changes in host and parasitic gene expression relating to neuropathology and resolution [Neuroinflammation]. Targeted transcriptomic analysis of C57BL/6 and BALB/c mice during progressive chronic Toxoplasma gondii infection reveals changes in host and parasitic gene expression relating to neuropathology and resolution [Neuroinflammation]
Toxoplasma gondii is a resilient parasite that infects a multitude of warm-blooded hosts and results in a lifelong chronic infection requiring continuous responses by the host. Chronic infection is ch
NIAID Data Ecosystem30
DataSheet1_Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway.ZIP
Acute lung injury (ALI) is a severe clinical disorder characterized by dysregulated inflammatory responses, leading to high rates of morbidity and mortality. Cinobufagin, a primary component isolated
NIAID Data Ecosystem10
Antibiotic-induced microbiome depletion ameliorates LPS-induced acute lung injury in mice.
In this research, treatment with ABX significantly attenuated LPS-induced lung injury of mice. Considering the key role of gut microbiota in immune system, it is likely that alternations in the gut mi
NIAID Data Ecosystem50
Correlation between M1/M2 polarization and functional groups.
Association of gees that are up- or downregulated in M1 and M2 cells polarisation (Figure 3A and B) with the functional groups defined from the analysis of the in vitro model of inflammation (Figure 2
Figshare2015-12-02 更新10
