Viral Metagenomics of Mosquito Populations in Guizhou Province, Southwest China

Mosquitoes are pivotal vectors of infectious diseases globally, significantly perpetuating the "poverty-disease-vector" cycle in underdeveloped regions. From 2021 to 2022, an extensive survey was conducted across eight regions in Guizhou Province of China, encompassing areas within Zunyi city (Bozhou, Chishui, Tongzi), Tongren city (Dejiang, Jiangkou, Songtao), Qianxinan Buyei and Miao Autonomous Prefecture (Xingren, Zhenfeng, Anlong, Wangmo), Bijie city (Qixingguan, Qianxi, Weining), Qiannan Buyei and Miao Autonomous Prefecture (Cengdu, Libo, Luodian), Qiandongnan Miao and Dong Autonomous Prefecture (Liping, Rongjiang, Congjiang), Anshun city (Xixiu), and Liupanshui city (Zhongshan, Panzhou). More than 40,000 adult mosquitoes were collected and subjected to metagenomic sequencing and bioinformatics analysis. The collected mosquitoes belonged to the genera Aedes, Anopheles, Armigeres, and Culex, with the dominant species identified as Aedes albopictus, Anopheles sinensis, Armigeres subalbatus, and Culex tritaeniorhynchus.