Targeting Histone K4 Trimethylation for Treatment of Cognitive and Synaptic Deficits of Mouse Models of Alzheimer's Disease (ChIP-seq)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE179999
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We performed chromatin immunoprecipitation sequencing (ChIPseq) to profile genome-wide occupancy of H3K4me3 in PFC from WT mice and P301S Tau mice Examination of the transcriptional changes of target genes related to the alteration of H3K4me3 of two 6 mo. old PS19(P301S), and two 6 mo. old control (C57BL/6 x C3H) mice from PFC tissue were compared.
创建时间:
2023-01-24



