Summary of striatal dopamine and substantia nigra (SN) dopaminergic neuron numbers in Klotho overexpressing mice (EFmKL48 or EFmKL46) and their wild type littermates after treatment with MPTP or saline.
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aMale Klotho overexpressing mice (lines EFmKL48 or EFmKL46) and wild type isogenic mice were administered MPTP at a cumulative dosage of 40 mg/kg. Mice were euthanized 7 days after last injection.*Student t-test, pSummary of striatal dopamine and substantia nigra (SN) dopaminergic neuron numbers in Klotho overexpressing mice (EFmKL48 or EFmKL46) and their wild type littermates after treatment with MPTP or saline.
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2015-12-03
