Epigenetic_landscape_of_expanded_potential_stem_cells. Epigenetic_landscape_of_expanded_potential_stem_cells

We described a new culture system that can expand the developmental potential of pluripotent stem cells to contribute efficiently to extraembryonic lineage development. To compare the epigenetic landscape of expanded potential stem cells (EPSCs) and standard embryonic stem cells, we performed ChIP-seq study on multiple histone modifications to establish the epigenetic landscape of EPSCs.