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资源简介：
Agxt off-target, Hao1 on/off-target
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创建时间：
2019-11-01
相关数据集
A Type II-B Cas9 nuclease with no detectable off-targets and reduced chromosomal translocations in vivo.
Streptococcus pyogenes Cas9 (SpCas9) and derived enzymes are widely used as components of CRISPR-Cas9 genome editing and engineering platforms. However, they exhibit promiscuous nuclease activity that
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Integrome signatures of lentiviral gene therapy for SCID-X1 patients
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Choice of Template Delivery Mitigates the Genotoxic Risk and Adverse Impact of Editing in Human Hematopoietic Stem Cells (RAAVIoli sequencing)
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In vivo evaluation of guide-free Cas9 induced genomic damage and transcriptome changes using pig models (RNA-seq). Sus scrofa
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Short read sequencing data used for RAAVioli validation
In this study, we validated RAAVioli, a bioinformatic framework designed to characterize adeno-associated virus (AAV) integration sites and genomic rearrangements. The data released here consist of Il
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