Intertidal ecosystems represent an untapped source of Actinobacteria. In this project, we have isolated Actinobacteria from intertidal sediments of Diu Island in the Arabian Sea. Representative potent
Streptomyces roseus produces Leupeptin, a potent and widely used protease inhibitor from the golden age of antibiotic discovery. The biosynthetic gene cluster for leupeptin biosynthesis was discovered