Dataset for 'Identification of immunodominant T cell epitopes in SARS-CoV-2 spike protein in Syrian hamsters'

This dataset contains all raw data underlying the main and supplementary figures of the manuscript “Identification of Immunodominant T Cell Epitopes in the SARS-CoV-2 Spike Protein in Syrian Hamsters” published in The Journal of Immunology. It includes measurements of T cell responses in Syrian hamsters immunized with a replication-defective ChAd-SARS-CoV-2-S vaccine encoding a pre-fusion–stabilized Wuhan-1 spike protein. The dataset also provides comparative T cell–response data following in vivo CD4 or CD8 depletion. In addition, it identifies key CD4 and CD8 epitopes within the most immunogenic regions of the spike protein.本数据集包含发表于《免疫学杂志》（The Journal of Immunology）的论文《叙利亚仓鼠SARS-CoV-2刺突蛋白免疫显性T细胞表位的鉴定》（Identification of Immunodominant T Cell Epitopes in the SARS-CoV-2 Spike Protein in Syrian Hamsters）的正图与补充图所依托的全部原始实验数据。数据集涵盖了接种编码预融合稳定化武汉-1刺突蛋白的复制缺陷型ChAd-SARS-CoV-2-S疫苗的叙利亚仓鼠的T细胞应答检测数据；同时提供了体内CD4或CD8耗竭后的T细胞应答对比数据；此外还鉴定了刺突蛋白最具免疫原性区域内的关键CD4和CD8表位。