Crystal Structure of ZipA in complex with indoloquinolizin 10b
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Crystal Structure of ZipA in complex with indoloquinolizin 10b Descriptor: Cell division protein zipA, N-{3-[(12bS)-7-oxo-1,3,4,6,7,12b-hexahydroindolo[2,3-a]quinolizin-12(2H)-yl]propyl}propane-2-sulfonamide Authors: Jennings, L.D, Foreman, K.W, Rush III, T.S, Tsao, D.H, Mosyak, L, Li, Y, Sukhdeo, M.N, Ding, W, Dushin, E.G, Kenny, C.H, Moghazeh, S.L, Petersen, P.J, Ruzin, A.V, Tuckman, M, Sutherland, A.G. Deposit date: 2004-01-07 Release date: 2005-01-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction BIOORG.MED.CHEM.LETT., 14, 2004
与吲哚并喹诺里嗪10b(indoloquinolizin 10b)结合的ZipA蛋白(ZipA)晶体结构 描述:细胞分裂蛋白ZipA,N-{3-[(12bS)-7-氧代-1,3,4,6,7,12b-六氢吲哚并[2,3-a]喹诺里嗪-12(2H)-基]丙基}丙烷-2-磺酰胺 作者:Jennings, L.D.、Foreman, K.W.、Rush III, T.S.、Tsao, D.H.、Mosyak, L.、Li, Y.、Sukhdeo, M.N.、Ding, W.、Dushin, E.G.、Kenny, C.H.、Moghazeh, S.L.、Petersen, P.J.、Ruzin, A.V.、Tuckman, M.、Sutherland, A.G. 沉积日期:2004-01-07 发布日期:2005-01-18 最后修改日期:2024-02-14 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.1埃(Å) 引用文献:《ZipA-FtsZ相互作用的吲哚并[2,3-a]喹诺里嗪-7-酮抑制剂的设计与合成》,《生物有机与药物化学快报(BIOORG.MED.CHEM.LETT.)》,第14卷,2004年



