The signature of liver cancer in host peripheral blood mononuclear cells and T cells DNA methylation. Homo sapiens

We demonstrate the feasibility of developing noninvasive DNA methylation biomarkers of early stages of HCC in the host T cells. These data are consistent with involvement of epigenetic modulation of the immune system in HCC. Overall design: Examination of DNA methylation signatures in peripheral blood mononuclear cells and T cells from liver cancer (stage 1-4), Hepatitis and control patients