Polybrominated diphenyl ethers (PBDEs) were used as flame-retardant additives starting 1965 and were recently withdrawn from commerce in North America and Europe. Approximately 1/5 of the total U.S. p
Shown are mean values calculated from at least three experiments ± SD. The cytotoxicity values (CC50) were for Hela H cells 8.54 ± 0.42 μM, for Hela R19 cells 7.07 ± 0.38 μM, and for RD, BGM, and Vero
Results of the analyses comparing predictive capabilities of GPR-based and S-GPR-based approaches using iMat, Gimme, Gonçalves et al. 2012 and MADE algorithms. (XLSX 309 kb)
CC50 and EC50 were determined by linear interpolation after addition of the drugs at 0 h (10 μM, 500 μM and 5mM for IC50) and (0.5 μM, 5 μM and 10 μM for EC5 Inhibitory concentrations of Immucillins a