Pseudomonas fluorescens kynurenine 3-monooxygenase (KMO) in complex with 3-{5-chloro-6-[(1R)-1-(6-methylpyridazin-3-yl)ethoxy]-1,2-benzoxazol-3-yl}propanoic acid

Pseudomonas fluorescens kynurenine 3-monooxygenase (KMO) in complex with 3-{5-chloro-6-[(1R)-1-(6-methylpyridazin-3-yl)ethoxy]-1,2-benzoxazol-3-yl}propanoic acid Descriptor: 3-[5-chloranyl-6-[(1~{R})-1-(6-methylpyridazin-3-yl)ethoxy]-1,2-benzoxazol-3-yl]propanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase Authors: Rowland, P. Deposit date: 2017-02-27 Release date: 2017-06-21 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase. Nat Commun, 8, 2017

本数据集为荧光假单胞菌（Pseudomonas fluorescens）犬尿氨酸3-单加氧酶（kynurenine 3-monooxygenase, KMO）与3-{5-氯-6-[(1R)-1-(6-甲基哒嗪-3-基)乙氧基]-1,2-苯并噁唑-3-基}丙酸的共结晶复合物。描述符：3-[5-氯-6-[(1R)-1-(6-甲基哒嗪-3-基)乙氧基]-1,2-苯并噁唑-3-基]丙酸、黄素腺嘌呤二核苷酸、犬尿氨酸3-单加氧酶。作者：Rowland, P.；保藏日期：2017-02-27；发布日期：2017-06-21；最后修改日期：2025-04-09；实验方法：X射线衍射（分辨率1.75埃）。引用文献：《急性胰腺炎靶点犬尿氨酸3-单加氧酶的差异化抑制剂的结构与机制基础》，《自然-通讯》，2017年，第8卷。