melanocortin 5 receptor (Mc5r) have various effects in immune responses. However, the involvement of Mc5r in ILC2 functions remains unclear. We identified the genes regulated by Mc5r in lung ILC2s dur
Here, we used the human ß cell line EndoC-ßH1 and analyzed its sensitivity to a lipo- and gluco-lipotoxic (high palmitate with or without high glucose) insult, as a way to model human ß cells in a T2D
Biallelic mutations in SLC29A3 cause histiocytosis-lymphadenopathy plus syndrome, also known as H syndrome (HS). HS is a complex disorder, with ~25% of patients developing autoinflammatory complicatio
Dying cells release Damage-Associated Molecular Patterns (DAMPs) that can initiate and perpetuate sterile inflammatory responses. However, the effect of DAMPs on macrophages biology remains unclear. W
