Mapk10

ENCODES a protein that exhibits ATP binding; JUN kinase activity; INVOLVED IN cellular hyperosmotic response; JNK cascade; JUN phosphorylation; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; FasL mediated signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); congestive heart failure (ortholog); Generalized Epilepsy (ortholog); FOUND IN glutamatergic synapse; perikaryon; postsynaptic Golgi apparatus; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2-ethoxyethanol; 2-methoxyethanol

编码一种具有ATP结合活性、JUN激酶活性，并参与细胞高渗反应、JNK级联反应、JUN磷酸化过程的蛋白质；参与c-Jun N-端激酶MAPK信号通路、FasL介导的信号通路以及血小板衍生生长因子信号通路；与阿尔茨海默病（同源物）、充血性心力衰竭（同源物）、全身性癫痫（同源物）相关；存在于谷氨酸能突触、胞体、突触后高尔基体中；与2,3,7,8-四氯二苯并呋喃、2-乙氧基乙醇、2-甲氧基乙醇相互作用。