Charting differences between tumors and normal tissue is a mainstay of cancer research. However, clonal tumor expansion from complex normal tissue architectures potentially obscures cancer-specific ev
Transcriptome sequencing was used to analyze changes in related signaling pathways and gene expression in Mutiple Myeloma cells when CHEK1 was overexptressed or knocked down. Examination of eight cel
Multiple myeloma (MM) is characterized by recurrent chromosomal translocations. The translocation t(4;14)(p16;q32) is one of the most common translocation in MMs, affecting 15% of patients, and is ass