DATA to support Dyrk1a function in glutamatergic neurons in mouse models of Mental Retardation Disease 7 (MRD7) and Down syndrome (or trisomy 21)

Four datasets are provided here to support the function of Dyrk1a in glutamatergic neurons in mouse models of Mental Retardation Disease 7 (MRD7) and Down syndrome (or trisomy 21): - RNAseq data to compare hippocampal expressed genes at postnatal day 30, in the complete inactivation of Dyrk1a in glutamatergic neurons using a Dyrk1a floxed-allele and the Camk2:Cre transgene - data from all the figures -data from all the supplementary figures -data from the quantitative proteomic analysis made from hippocampal extract of wt, Dyrk1a heterozygote, Dp(16)1Yey and Dp(16)1Yey with only two functional copies of Dyrk1a Detailed information are available in the article by Brault et al 2021, deposited in Biorachiv https://doi.org/10.1101/2021.05.01.442242