Best fit parameters for the biphasic activation-inhibition dose-response curves with DAPTa.

The units for all activity measurements are: Aβ 1-40 secreted in pM per 106 cells.athe best fit values ± standard error were calculated using nonlinear regression and eqn.1.btwo sigma confidence intervals as indicated in methods section [34].cnot applicable, or the corresponding values could not be resolved in the current experiments.dno activation is observed when DNA concentration is higher than 250 ng/ml. Thus starting at 250 ng/ml the best fit values ± standard error were calculated using a nonlinear regression and eqn.2.