Gene expression profile at single nuclei resolution of aortas from Ldlr-/- mice with or without defective hepatic glutaminolysis

Metabolic dysregulation, including perturbed glutamine-glutamate homeostasis, is a hallmark of atherosclerotic diseases. We used single nuclei RNA sequencing (snRNA-seq) to analyze the impact of defective hepatic glutaminolysis on cell diversity in atherosclerotic aorta. single-nuclei transcriptomics (snRNA-seq) from control and Ldlr-/-Gls2shRNA aortas