RAS and CPSa protection upon P. berghei sporozoite challengeb.
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aCPS mice received 24-days chloroquine treatment. All immunized mice were challenged 17 days after CQ treatment.bCumulative data from three experiments. In two experiments, mice were challenged by i.v. injection of 10.000 WT sporozoites. In one experiment, mice were challenged by bites of 5–11 infected mosquitoes. Protection was defined as negative blood-smears at day 21 after challenge.
创建时间:
2015-12-02



