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Transcriptomic characterization of sotorasib-resistant tumors in Kras-G12C/Trp53-driven LUAD in genetically engineered mice

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NIAID Data Ecosystem2026-05-01 收录
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To characterize sotorasib resistance in lung adenocarcinomas (LUAD), we generated genetically engineered mice (Kras-G12C, Trp53-KO) and compared the transcriptional profiles of untreated and sotorasib-resistant tumors Comparative gene expression profiling analysis of RNA-seq data for sotorasib-resistant lung tumors in mice

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2023-06-05
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