Subchondral bone fatigue injury in the parasagittal condylar grooves of the third metacarpal bone in Thoroughbred racehorses elevates site-specific strain concentration

Condylar stress fracture of the distal end of the third metacarpal/metatarsal (MC3/MT3) bones is a major cause of Thoroughbred racehorse injury and euthanasia worldwide. Functional adaptation to exercise and fatigue damage lead to structural changes in the subchondral bone that include increased modeling (resulting in sclerotic bone tissue) and targeted remodeling repair (resulting in focal resorption spaces in the parasagittal groove). Whether these focal structural changes, as detectable by standing computed tomography (sCT), lead to elevated strain at the common site of condylar stress fracture has not been demonstrated. Therefore, the goal of the present study was to compare full-field three-dimensional (3D) strain on the distopalmar aspect of MC3 bone specimens with and without focal subchondral bone injury (SBI). Thirteen forelimb specimens were collected from racing Thoroughbreds for mechanical testing ex vivo and underwent sCT. Subsequently, full-field displacement and strain ..., Please refer to the linked research article for detailed explanation of the methods., , # Subchondral bone fatigue injury in the parasagittal condylar grooves of the third metacarpal bone in Thoroughbred racehorses elevates site-specific strain concentration [https://doi.org/10.5061/dryad.8w9ghx3sk](https://doi.org/10.5061/dryad.8w9ghx3sk) This dataset contains raw and processed experimental data from mechanical testing of condyles of MC3 bone of Thoroughbred racehorses, and their CT densities acquired with Equina Asto CT. For best results, download all the files, scripts, and zipped folders (unzip them after) and put them all in the same directory. ## Description of the data and file structure 1- Raw experimental data are organized as follows: Name of folders that contain the unprocessed raw experimental data begins with *rawData_* and continues with the condyle ID. For example: *rawData_POD2*, *rawData_CTRL5*, etc. These folders include images of the calibration object that is a grid of 2-mm spaced dots attached to a 1.5 inch (38.1 mm) diameter cylinder, testing video...第三掌骨/跖骨（third metacarpal/metatarsal (MC3/MT3)）远端髁部应力性骨折是全球范围内纯血赛马受伤与安乐死的主要诱因。运动带来的功能适应与疲劳损伤会引发软骨下骨结构改变，具体包括骨建模增强（形成硬化骨组织）以及靶向性重塑修复（在矢旁沟内形成局灶性吸收间隙）。目前尚未明确，这些可通过站立式计算机断层扫描（standing computed tomography, sCT）检测到的局灶性结构改变，是否会导致髁部应力性骨折好发部位的应变水平升高。因此本研究的目的是对比存在与不存在局灶性软骨下骨损伤（subchondral bone injury, SBI）的MC3骨标本掌侧远端区域的全场三维（3D）应变情况。我们从参赛纯血马身上采集了13件前肢标本用于离体力学测试，并完成了sCT扫描。后续获取了全场位移与应变数据……详细实验方法请参阅关联研究论文。 # 纯血赛马第三掌骨矢旁髁部软骨下骨疲劳损伤升高局部应变集中 https://doi.org/10.5061/dryad.8w9ghx3sk 本数据集包含纯血赛马MC3骨髁部力学测试的原始与处理后实验数据，以及使用Equina Asto CT采集的CT密度数据。 为获得最佳使用效果，请下载所有文件、脚本与压缩文件夹（下载后完成解压），并将所有内容置于同一目录下。 ## 数据与文件结构说明 1. 原始实验数据的组织方式如下： 未处理的原始实验数据所在文件夹名称以`rawData_`开头，后续接髁部编号，例如`rawData_POD2`、`rawData_CTRL5`等。此类文件夹包含校准体的相关图像——该校准体为安装在直径1.5英寸（38.1毫米）圆柱上、间距2毫米的点阵网格，以及测试视频……