insulin resistant duodenum vs. non-insulin resistant duodenum

Transcriptional profiling of duodenum from non-obese patients and patients with morbid obesity comparing non-insulin resistance vs. insulin resistande. Goal was to determine the involvement of the duodenum in the development of insulin resistance and the possible influence of obesity. Four-condition experiment: non-obese patients with low insulin resistance (n=6), non-obese patients with high insulin resistance (n=7), patients with morbid obesity and low insulin resistance (n=7) and patients with morbid obesity and high insulin resistance (n=8).