Dementia Comparison: VaD vs. AD vs. Controls

Gene expression profiling was performed on frontal and temporal cortex from vascular dementia (VaD), Alzheimer's disease (AD), and non-demented controls (Control) obtained from the University of Michigan Brain Bank. Controls and AD cases had no infarcts in the autopsied hemisphere. Vascular dementia cases had low Braak staging. Each sample (VaD=8), (AD=12), (Controls=11) was run, at a minimum, in duplicate with a dye swap (Cy3/Cy5) on Agilent Human 8x60k v2 microarrays. These are dual channel arrays, but have been processed as a single channel analysis. Normalized log2 signal is provided for each sample. Raw files are included in a tar archive on the series record. Please see 'Description' field for the name of the raw file for each sample.