Effect of α-tomatine and curcumin on apoptosis of cultured prostate cancer cells.

LNCaP, VCaP, PC-3 and RWPE-1 cells were seeded at a density of 0.2 × 105 cells/ml and incubated for 24 h. The cells were then treated with α-tomatine (α-T; 1 μM) or curcumin (Cur; 5 or 10 μM) alone or in combination for 48 h. Apoptosis was determined by morphological assessment. Each value is the mean ± S.E from three experiments.Effect of α-tomatine and curcumin on apoptosis of cultured prostate cancer cells.