Amino acid substitutions and resulting haplotypes in four studied genes from 51 parasite isolates.

†denotes the reference haplotype in 3D7; Letters in bold indicate mutated amino acids; - indicates deletion of the residue. No. (%) indicates the number and percentage of isolates harboring these mutations or haplotypes. *The mdr6 haplotypes: R1 repeats, number of N at positions 103–110; R2, number of NI at positions 267–270, R3, number of NIN at positions 717–734; the tri-peptide SIN at position 735–737 are shown as + (present) or – (deleted).