AGFG1 binds VAMP7
收藏reactome.org2025-01-15 收录
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AGFG1, also known as HRB (HIV-1 Rev-binding), is a clathrin adaptor and ArfGAP that interacts with the R-SNARE VAMP7 to mediate its endocytosis from the plasma membrane (Pryor et al, 2008; Chaineau et al, 2008). AGFG1 also interacts with a number of other endocytic proteins such as EPS15, EPS15R, FCHos and ITSNs (Doria et al, 1999; Salcini et al, 1997; Schmid et al, 2006; Umasankar et al, 2012).
AGFG1,亦称HRB(HIV-1 Rev结合蛋白),是一种衣壳蛋白适配体和ArfGAP,它能与R-SNARE VAMP7相互作用,介导其从质膜(Pryor 等人,2008;Chaineau 等人,2008)的内吞作用。AGFG1还与多种内吞蛋白相互作用,如EPS15、EPS15R、FCHos和ITSNs(Doria 等人,1999;Salcini 等人,1997;Schmid 等人,2006;Umasankar 等人,2012)。
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