Analysis of the taxonomic profile of the intestinal microbiota in patients with alcoholic liver cirrhosis and acute-on-chronic liver failure (ACLF) in western Mexico (dataset 1/2)

ACLF is a severe stage of liver cirrhosis, characterized by multiple organ failure, systemic inflammation, and high short-term mortality. The intestinal microbiota (IM) influences its pathophysiology; however, as of the time of main publication, there were no studies in Latin American populations. Therefore, we analyzed IM and its relationships with several clinical outcomes. The IM was characterized using excreted fecal samples, from which DNA was extracted using Quick-DNA Fecal/Soil Microbe Miniprep Kit (Zymo Research); then, sequencing was achieved using using standard 16S-rRNA V3-V4 Illumina protocol (2x300 bp). This record comprises the first data set (1/2).