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Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination Descriptor: (~{E})-3-(2,4-dichlorophenyl)prop-2-enoic acid, ACETIC ACID, CARBONIC ANHYDRASE 2, ... Authors: Woods, L.A, Dolezal, O, Ren, B, Ryan, J.H, Peat, T.S, Poulsen, S.A. Deposit date: 2015-11-15 Release date: 2016-03-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59, 2016

天然状态质谱法、表面等离子体共振法与X射线晶体学作为片段筛选组合时相关性极强。 描述符:(E)-3-(2,4-二氯苯基)丙-2-烯酸、乙酸、碳酸酐酶2(Carbonic Anhydrase 2)等 作者:Woods L.A、Dolezal O、Ren B、Ryan J.H、Peat T.S、Poulsen S.A 提交日期:2015-11-15 发布日期:2016-03-02 最后修改日期:2024-01-10 实验方法:X射线衍射(分辨率1.59埃) 引用文献:《天然状态质谱法、表面等离子体共振法与X射线晶体学作为片段筛选组合的相关性研究》,《药物化学杂志》(J.Med.Chem.),第59卷,2016年
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2015-11-15
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