*CD-1 mice received IV single injections of MTM-SK, MTM-SDK and MTM or repeated injections of the compounds every two (q2d×10) or three days (q3d×10) for a total of 10 injections. ND, not determined.
Table A in S1 File, the influence of the TRF on the organ coefficient of BALB/c nude mice. Table B in S1 File, effects of TRF on indexes of hematology in the nude mice. Table C in S1 File, effects of
Aim: Aur0101 is a cytotoxic and small-molecule microtubule depolymerizing agent, and is the payload conjugated to antibody–drug conjugate PYX-201. Developing and validating a sensitive bioanalytical m