longevity-db/sc-human-blood-aging-atlas

该数据集是一个健康成年人外周血单核细胞（PBMC）的多模态单细胞测量数据集，涵盖了166名年龄在25至85岁之间的健康个体，跨越了3年的时期。数据集通过单细胞RNA测序、TCR/BCR分析以及20重蛋白条形码技术，包含了约200万个高质量的单细胞，被注释为50多种不同的免疫细胞类型。数据集可用于探索年龄相关的免疫重构，并支持下游的机器学习和计算建模工作。

This dataset is a multi-modal single-cell measurement dataset of peripheral blood mononuclear cells (PBMCs) from 166 healthy individuals aged 25 to 85, spanning a 3-year period. Profiled using single-cell RNA sequencing, TCR/BCR profiling, and 20-plex protein barcoding, the dataset contains ~2 million high-quality single cells annotated into 50+ distinct immune cell types. It is a rich resource for exploring age-associated immune remodeling and supports downstream machine learning and computational modeling efforts in aging, immunology, and single-cell systems biology.