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Effects of allopurinol and febuxostat on uric acid transport and transporter ...

B2FIND2026-04-29 收录

尿酸代谢药理

动脉粥样硬化机制

数据链接：

https://b2find.eudat.eu/dataset/a2858b4f-a2c8-563c-b402-26c4d673fc02 数据链接链接失效反馈

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Uric acid induces radical oxygen species formation, endothelial inflammation, and endothelial dysfunction which contributes to the progression of atherosclerosis. Febuxostat and...

应用场景：

动脉粥样硬化机制

单细胞RNA测序

Raw fastq files from paired-end, Illumina-based sequencing on NovaSeq6000 Apoe-/- mice were fed a western diet for 4 weeks and administered saline or nt-LNA (30 mg/kg) weekly. After 4 weeks, aortic a

NIAID Data Ecosystem80

Annexin A8 deficiency delayed atherosclerosis progression. Annexin A8 deficiency delayed atherosclerosis progression

动脉粥样硬化机制

AnnexinA8功能研究

Background Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipids and leukocytes within the arterial wall. By investigating the aortic transcriptome of atheroscl

NIAID Data Ecosystem70

Top 10 most up-regulated and down-regulated genes during oxLDL-induced foam cell formation.

动脉粥样硬化机制

基因表达谱分析

Top 10 most up-regulated and down-regulated genes during oxLDL-induced foam cell formation.

NIAID Data Ecosystem40

Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective. doi: 10.1038/nm.4109

动脉粥样硬化机制

平滑肌细胞转录组

The multiple claims about reactivation of the embryonic stem cell (ESC) pluripotency factor OCT4 in somatic cells are highly controversial due to the fact that there is no direct evidence that OCT4 ha

NIAID Data Ecosystem70

Profile of IL-6 and TNF in Foam Cell Formation: An Improved Method Using Fluorescein Isothiocyanate (FITC) Probe

动脉粥样硬化机制

炎症因子检测

Abstract Background The formation of foam cells occurs due to the increase in low-density plasma lipoprotein (LDL) and dysregulation of inflammation, which is important for the development of athero

NIAID Data Ecosystem60

Effects of allopurinol and febuxostat on uric acid transport and transporter ...

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