Rhodium-Catalyzed Tandem Heterocyclization and Carbonylative [(3+2)+1] Cyclization of Diyne-enones

A simple and highly efficient rhodium-catalyzed tandem heterocyclization and carbonylative [(3+2)+1] cyclization reaction of readily available diyne-enone and carbon monoxide was developed, leading to a novel polycyclic furan scaffold. Synthetically useful highly substituted phenols can also be easily prepared via a straightforward one-pot synthetic strategy.