Purpose: Identify differentially expressed genes in placental samples from early-onset (EO) IUGR, EO-PE, as well as pregnancies complicated by both EO-PE and EO-IUGR Methods: Isolated total RNA from h
Chagas disease, caused by Trypanosoma cruzi, affects over seven million people worldwide. Vertical transmission during pregnancy contributes to the urban spread of the disease, including in non-endemi
Trypanosoma cruzi isolates naturally adapted to congenital infection display a unique strategy of transplacental transmission. Transcriptomic analysis of placental response to parasite passage reveale
Preeclampsia (PE) is a serious pregnancy associated disorder. Recently, it has been proposed that the role of the placenta differ between the two sub-groups early- and late-onset PE. To further elucid
Additional file 10. Gene sets enriched in both birth weight and U-As analyses in A) female and B) male fetal placenta at FDR < 0.05. Gene sets showing opposite directions of association in 9A) are ast